How small changes in walking technique may help treat knee osteoarthritis
Gait analysis and pain measures show that subtly adjusting the angle of the foot during walking may reduce knee pain caused by osteoarthritis. This approach may also slow progression of the condition, an incurable disease in which the cartilage cushion inside a joint breaks down.
Platelet-Rich Plasma-Contained Drug Delivery Systems to Treat Orthopedic Injuries
Platelet-rich plasma (PRP), an autologous biocomponent, has been clinically applied in tissue regeneration and repair, yet it faces challenges such as unclear mechanisms, side effects, and uncontrollable release. This review provides evidence for further clinical research on PRP and its associated drug delivery strategies in orthopedics.
XSTEM’s Knee Osteoarthritis Stem Cell Trial: Mid-Study Update, Safety and Positive Efficacy
Xintela has released interim data from its ongoing clinical study evaluating its stem cell product, XSTEM, in patients with knee osteoarthritis. XSTEM is an allogeneic adipose stem cell therapy, consisting of integrin α10β1-selected mesenchymal stem cells. At 18 months post-treatment, the company reports demonstrated safety and positive efficacy, including statistically significant and clinically meaningful improvements in knee pain and knee function.
Total Knee Arthroplasty After a Previous Patellectomy: A Case Report With a Six-Month Follow-Up and a Review of the Literature
Total knee arthroplasty (TKA) is a widely performed surgical intervention for the treatment of knee osteoarthritis. However, various patient-specific factors altering the biomechanics can influence the surgical technique and the postoperative outcomes. In this case report, a patient is presented who was admitted to our hospital with chronic left knee pain caused by osteoarthritis, with a history of patellectomy after a traumatic event 35 years ago.
Clinical results of reverse shoulder arthroplasty after failed arthroscopic rotator cuff repair compared to primary cases: a case–control study
Although reverse shoulder arthroplasty (RSA) is a popular treatment, its efficacy in patients with failed rotator cuff repair (ARCR) remains unclear. In this study, we aimed to evaluate the clinical results of RSA for following failed ARCR. We hypothesized that RSA after failed ARCR would lead to improved clinical outcomes comparable to those of RSA performed without prior surgeries.
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