Outcomes of total knee arthroplasty in people with diabetes: An overview of systematic reviews and meta-analysis
Total knee arthroplasty (TKA) in people with diabetes is associated with increased risks of postoperative complications. This review evaluates how diabetes influences complication rates and overall outcomes following TKA.
8 Tips for Healthy Bones
It’s a fact of life: As you age, your bones become thinner and lose their density. Fortunately, you can take steps early on to strengthen your bone health and prevent osteopenia (bone thinning) and osteoporosis (late-stage bone loss). Bone health starts with proper nutrition, exercise and healthy lifestyle choices.
Corticosteroids Versus Platelet-Rich Plasma Injections for Knee Osteoarthritis: Where is there More Evidence? A Systematic Review of 60 Years of Literature
PRP injections for knee OA have been documented in more studies and in larger patient numbers compared with CS injections. The higher number of high-level trials for PRP, combined with the lower safety and efficacy documented for CS by previous meta-analyses directly comparing the two products, strongly suggests reconsidering current guidelines that favor CS, highlighting PRP’s body of evidence and the potential role in the effective and safe treatment of knee OA.
Stem Cell Therapies for Spinal Cord Injury in Humans: A Review of Recent Clinical Research
Recently, cell transplantation has emerged as a promising treatment for spinal cord injury (SCI). Over the past decade, numerous clinical studies of SCI have been conducted using various types of cells, including fetal neural stem/progenitor cells (NS/PCs), pluripotent stem cell-derived NS/PCs, mesenchymal stem/stromal cells (MSCs), olfactory ensheathing cells, and Schwann cells. Promising results have been reported for patients with subacute SCI, especially in studies involving MSCs, such as those conducted with Stemirac, although no universally recognized breakthroughs have been achieved. Allogenic NS/PCs may offer advantages over autologous MSCs because they have the potential for cell engraftment within the spinal cord and can be prepared in advance, facilitating their administration during the hyperacute phase.
Quadriceps and hamstring muscles strength differences in adolescent and adult recreational athletes 6 months after autograft bone-patellar-tendon-bone anterior cruciate ligament reconstruction: A retrospective study
Knee muscle strength recovery after anterior cruciate ligament reconstruction (ACLR) is crucial for a safe return to sport (RTS) but it is poorly described in the adolescent population. Therefore, we compared the knee muscle strength at 6 months post-surgery in adults and adolescents. We hypothesized a greater muscular strength in adolescents 6 months after ACLR.
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