What to know about knee stiffness
A stiff knee is a common complaint, especially among older adults and those who are very physically active. Knee stiffness can occur due to low flexibility or muscular imbalances in the legs, injury, or arthritis. The most suitable treatment for knee stiffness depends on the underlying cause.
Clinical Implications of Post-operative Haemoglobin Levels in Total Hip and Knee Arthroplasty
Current trends towards minimally invasive surgery and enhanced recovery encourage patients to mobilise and be discharged on the same day following total hip and knee arthroplasty (THA/TKA). The aim was to evaluate the value of current practice in measuring day 1 postoperative haemoglobin levels and stratify patient groups for whom this may be useful.
How small changes in walking technique may help treat knee osteoarthritis
Gait analysis and pain measures show that subtly adjusting the angle of the foot during walking may reduce knee pain caused by osteoarthritis. This approach may also slow progression of the condition, an incurable disease in which the cartilage cushion inside a joint breaks down.
Platelet-Rich Plasma-Contained Drug Delivery Systems to Treat Orthopedic Injuries
Platelet-rich plasma (PRP), an autologous biocomponent, has been clinically applied in tissue regeneration and repair, yet it faces challenges such as unclear mechanisms, side effects, and uncontrollable release. This review provides evidence for further clinical research on PRP and its associated drug delivery strategies in orthopedics.
XSTEM’s Knee Osteoarthritis Stem Cell Trial: Mid-Study Update, Safety and Positive Efficacy
Xintela has released interim data from its ongoing clinical study evaluating its stem cell product, XSTEM, in patients with knee osteoarthritis. XSTEM is an allogeneic adipose stem cell therapy, consisting of integrin α10β1-selected mesenchymal stem cells. At 18 months post-treatment, the company reports demonstrated safety and positive efficacy, including statistically significant and clinically meaningful improvements in knee pain and knee function.
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